The Avmacol® Story

For more than a decade, researchers at Nutramax Laboratories have been investigating the phytochemical sulforaphane. Since we started, findings from across the health sciences began to confirm what our own work had suggested: for researchers committed to making true health accessible in the modern world, the potential benefits of sulforaphane were too great to ignore.

Our lives today present our bodies with a wide array of new toxins and stressors. The food we eat, the air we breathe, and the environments we live and work in all put stress on our cells and immune systems. Sulforaphane, which broccoli sprouts and other cruciferous veggies help the body produce naturally, helps our cells fight off those threats, giving our natural immune and detoxification systems the support they need to thrive.

The Avmacol® brand has been selected for use in more sulforaphane human clinical trials than any other supplement1 and Avmacol® Extra Strength harnesses the synergistic properties of maitake mushroom extract to heighten the support for your cells. If you’re looking for a convenient, safe way to support your body through the challenges of modern life, you’re looking for Avmacol®. Unleash the power of broccoli with Avmacol.

Backed by Research

At Nutramax Laboratories we hold ourselves to the very highest standards of research—both in supporting peer-reviewed studies across disciplines and in replicating findings in our own work. Our rigorous approach is driven by a desire to provide families with supplements they can truly trust. Both in quality of ingredients and research, our laboratory practices set the standard for our industry.

The Avmacol® brand has been selected for use in more sulforaphane human clinical trials than any other supplement1, because we're committed to driving research forward and we hold our products to the highest standard.

The Avmacol® Community

For families today, living healthy, balanced lives in harmony with our body’s natural processes is more complicated than ever. Our mission is to provide opportunities that make it easier to relieve stress on families all the way down to the cellular level.

The Avmacol® Difference

As the leading supplement in clinical research around sulforaphane, Avmacol® is
backed by evidence you can trust. And our Sulforaphane Production System®
guarantees the presence of myrosinase, an important precursor enzyme for your
immune system.

  • Sulforaphane can only be produced in the body with the antioxidant glucoraphanin and the enzyme myrosinase. Our patented Sulforaphane Production System® was designed to deliver these necessary building blocks with every serving.

  • The Sulforaphane Production System® was developed by our scientists at Nutramax Laboratories with the help of a leading sulforaphane researcher with two decades of experience examining this vital phytochemical.

     Avmacol® Extra Strength

    Avmacol® Extra Strength and Your Immune Health

    The world today is hard on our bodies. Factory-farmed meats.  Automobile exhaust. Constantly spiking cortisol from jobs that  intrude on our lives like never before. Even for those of us who are truly committed to our health and wellness, maintaining a natural balance is a challenge. We hope to make it easier with Avmacol®.

    Make Avmacol® a Part of Your Wellness Routine

    By giving your body what it needs to produce sulforaphane, you’re  helping your cells fight inflammation and oxidative stress associated  with a wide range of potential health issues. You know that feeling you get when you finish a good jog or a hike? When your mind is clear  and you’re breathing a little easier? That’s how your cells feel when  they’re able to produce sulforaphane. Think of Avmacol® as taking  your cells out for a jog. Or like eating a salad for your immune system.  A simple, safe part of your wellness routine that helps you feel and be  your best.

    Are You Ready to Unleash the Power of Broccoli®?

    YES,I'M READY!

    Your Body's Detoxification Process

    How does your body naturally detoxify certain environmental threats?

    Every day you are exposed to a barrage of chemicals in the environment that are not naturally found in your body. These chemicals can take a toll on your overall health and wellness. Thankfully, your body has anatural detoxification systemto help get rid of harmful substances that you are exposed to in the environment, or from household products and even the food you eat. Your detoxification system has 2 phases: First, when chemicals enter your body, Phase 1 detoxifying enzymes begin to process them into metabolites, which may be potentially harmful. Next, Phase 2 detoxifying enzymes change the potentially harmful metabolites into water-soluble compounds that can be easily excreted from your body.

    Why is detoxification support important?

    The potentially harmful metabolites that are left behind by the first phase of your body’s natural detoxification process can be much more toxic than the original chemical. As long as these metabolites are swirling around in our cells they can cause damage to our DNA, proteins, and lipids. A good way to think of the metabolites is to consider holding a lit match: the longer you hold the match without blowing it out, the more likely you are to get burned. Therefore, their removal from the body is of vital importance to our overall health and general wellness.

    What are natural killer cells?

    A natural killer cell is a white blood cell with the ability to cause cells with foreign material to self-destruct.

    The Science Behind Avmacol®

    What is sulforaphane?

    Sulforaphane is a phytochemical (a phytochemical is a biologically active compound of plant or vegetable origin) that helps increase the production of important Phase 2 detoxifying enzymes, promoting your body’s natural detoxification process, thereby supporting the elimination of potentially harmful metabolites. These harmful metabolites may cause damage to DNA, proteins and lipids in your cells. Sulforaphane is formed when a compound called glucoraphanin is transformed by an enzyme called myrosinase. Both glucoraphanin and active myrosinase enzyme are needed for sulforaphane production.

    What is glucoraphanin?

    Glucoraphanin is a compound that is present in many cruciferous vegetables, most notably in broccoli. It is an essential ingredient needed for sulforaphane production because it is sulforaphane’s direct precursor. The myrosinase enzyme processes glucoraphanin into sulforaphane.

    What is myrosinase and why is it so important?

    Myrosinase is an important enzyme required to convert glucoraphanin into sulforaphane. Additionally, it can be found in cruciferous vegetables, though it can become inactivated during the cooking process. It is important to remember thatactive myrosinase enzyme is necessary to convert glucoraphanin into sulforaphane.

    Can I eat a lot of broccoli and get the benefits of sulforaphane?

    Sulforaphane production is not predictable when eating broccoli. The levels of glucoraphanin and the active myrosinase enzyme vary greatly in vegetables you would typically buy at the market due to seed quality, soil composition, and other factors. Additionally, the myrosinase enzyme can be destroyed during the cooking process. Therefore, simply eating cruciferous vegetables, like broccoli,does not provide reliable amounts of glucoraphanin and the myrosinase enzyme and thus does not guarantee that your body will make sulforaphane.

    What is the Sulforaphane Production System®?

    The Sulforaphane Production System® is the foundation of the entire Avmacol® product line and includes the essential
    ingredients needed to promote sulforaphane production – glucoraphanin and active myrosinase enzyme.

    Avmacol® Extra Strength

    What is Avmacol® Extra Strength?

    Avmacol® Extra Strengthis a patented,sulforaphane-producing supplementthat works in combination with Maitake mushroom extract (Grifola Frondosa) to support your body’s natural detoxification processbetter than sulforaphane alone.1Avmacol® Extra Strength provides glucoraphanin and active myrosinase enzyme which are the essential ingredients needed for sulforaphane production.

    How does Avmacol® Extra Strength work?

    Avmacol® Extra Strength deliversglucoraphanin and active myrosinase enzyme, which are the ingredients needed for sulforaphane production, along with the Maitake mushroom extract (Grifola frondosa). This combination helps increase the production of Phase 2 detoxifying, thereby supporting the elimination of potentially harmful metabolites.* A good way to think about the mechanism of action of sulforaphane in our cells is as having the effect of turning up a “dimmer switch” which controls Phase 2 enzyme production in cells. TheMaitake mushroom extract works in combination with sulforaphaneto support your body’s natural detoxification process better than sulforaphane alone.
    1Maitake mushroom extract has also been shown in published studies to support the immune system.

    Is Avmacol® Extra Strength gluten-free?

    Yes, Avmacol® Extra Strength is gluten-free.

    Is Avmacol® Extra Strength vegetarian?

    Yes, Avmacol® Extra Strength is a vegetarian formula.

    Does Avmacol® Extra Strength contain any artificial colors?

    No, Avmacol® Extra Strength does not contain any artificial colors.

    How should I take Avmacol® Extra Strength?

    Take 1 (one) tablet per day with a meal.